Recent Advances in Biomedical Electronics and Biomedical Informatics

نویسندگان

  • CASTILLO
  • SIDORENKO
  • ORTEGA
  • VEGA
  • and SOTO
چکیده

In this work we present a mathematical model of the informative process of the biosensor of angular acceleration (vestibular system in the inner ear). The functional and numerical parameters of the model have been identified by physiological and morphological experiments in the inner ear of amphibians and mammals. The model developed is a compartmental-type model in which we considered all the stages of the sensory activation process in the biosensor of angular acceleration. We performed a comparative analysis between our model and the mathematical model of Fernandez and Goldberg (1971), in which they described the change of the firing frequency of primary afferent neurons in response to the angular acceleration of the head about the vertical axis. The comparative analysis of both models indicates that our model more appropriately reproduce the fast responses of the vestibular system than Fernandez and Goldberg model; in addition, the parameters used in our model have physiological meaning. Key-Words: Mechanical stimulus, hair cell, primary neuron, vestibular mechanoreceptor, afferent impulses

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تاریخ انتشار 2009